Description
Ifosfamideisanitrogenmustardalkylatorthatexhibitsanticancerchemotherapeuticactivity.Ifosfamideisclinicallyusedtotreatvariouscancers.Becauseifosfamideisverycytotoxic,itisoftenco-admiNISTeredwithcytoprotectiveagentssuchasMESNA.
References
VincenziB,FrezzaAM,SantiniD,etal.Newtherapiesinsofttissuesarcoma.ExpertOpinEmergDrugs.2010Jun;15(2):237-48.PMID:20465449.
NissimI,HorynO,DaikhinY,etal.Ifosfamide-inducednephrotoxicity:mechanismandprevention.CancerRes.2006Aug1;66(15):7824-31.PMID:16885387.