进口Tocris试剂盒，血清清关 Tocris Bioscience产品促销,Tocris/NBD 556/5811/50/50 mg,临床研究,其它试剂,其它,,Tocris Bioscience蚂蚁淘商城

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Tocris/NBD 556/5811/50/50 mg

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Tocris

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5811/50

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4000-520-616

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Description:CD4mimetic;blocksHIV-1cellentry

ChemicalName:N¹-(4-Chlorophenyl)-N²-(2,2,6,6-tetramethyl-4-piperidinyl)ethanediamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CD4mimetic(IC₅₀valuesareinlowmicromolarrange,dependentoncelltypeandHIVstrain).RecognizesandinducesstructuralchangesinHIV-1envelopeproteingp120,analogoustoCD4binding.InhibitsHIV-1cellentryinCXCR4andCCR5expressingcelllines,byblockingvirus-cellandcell-cellfusion.

TechnicalData

M.Wt	337.84
Formula	C₁₇H₂₄ClN₃O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	333353-44-9
PubChemID	1570601
InChIKey	ZKXLQCIOURANAD-UHFFFAOYSA-N
Smiles	CC1(CC(NC(C(NC2=CC=C(C=C2)Cl)=O)=O)CC(C)(N1)C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	33.78	100
	ethanol	6.76	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight337.84.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.96mL	14.8mL	29.6mL
5mM	0.59mL	2.96mL	5.92mL
10mM	0.3mL	1.48mL	2.96mL
50mM	0.06mL	0.3mL	0.59mL

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